The smart Trick of Actavis promethazine codeine That Nobody is Discussing
Wiki Article
Promethazine HCl and Codeine Phosphate Oral Remedy must be made use of with warning in clients with bone- marrow melancholy. Leukopenia and agranulocytosis happen to be described, ordinarily when promethazine has become used in Affiliation with other known marrow-poisonous brokers.
Drug interactions, like a heightened incidence of extrapyramidal outcomes, are claimed when some MAOI and phenothiazines are used concomitantly.
Indeed this webpage is useful No this page is not practical Thanks to your suggestions Report a problem with this webpage
As a result of possibility of respiratory melancholy, stay away from the use of opioid antitussives, such as Promethazine HCl and Codeine Phosphate Oral Remedy in patients with compromised respiratory purpose, patients at risk of respiratory failure, As well as in aged, cachectic, or debilitated patients.
Correct evaluation of your client, suitable prescribing procedures, periodic re-evaluation of therapy, and right dispensing and storage are ideal steps that enable to limit abuse of opioid medication.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people fewer than 6 years of age, due to the fact the combination may well result in lethal respiratory depression In this particular age inhabitants. It is crucial that promethazine hydrochloride and codeine phosphate syrup is measured with an correct measuring machine (see Safeguards-Details for Sufferers).
Take promethazine/codeine particularly as prescribed. Notify your Health care service provider in the event you feel that promethazine/codeine is not really Doing work. Contact your healthcare service provider immediately or head over to the closest crisis home In case you have any of the subsequent major indicators.
Promethazine/codeine can also be useful for other situations as determined by your Health care service provider.
Respiratory despair bringing about arrest, coma, and Loss click here of life has happened with the use of codeine antitussives in youthful young children, particularly from the below-one particular-calendar year infants whose power to deactivate the drug just isn't entirely made.
Released reports with codeine have claimed here inconsistent conclusions and have important methodological constraints (see Data). You can find reports of respiratory depression when codeine is utilised during labor and shipping and delivery (see Clinical Criteria).
Stimulation could be obvious, specifically in young children click here and geriatric clients. Convulsions may well rarely arise. A paradoxical response has been noted in young children receiving single doses of 75 mg to 125 mg orally, click here characterized here by hyperexcitability and nightmares.
Inform your medical professional For anyone who is Expecting or Imagine you could be Expecting. Throughout pregnancy, this products just isn't suggested. It may well damage an unborn little one. Discuss with your health practitioner in regards to the challenges and benefits of this medication. See also Warning segment.
Little ones Postmarketing instances of respiratory depression, like fatalities, are actually noted with utilization of promethazine in pediatric sufferers. Concomitant administration with other respiratory depressants may well increase the danger of respiratory melancholy.
The concomitant usage of opioids with other prescription drugs that have an affect on the serotonergic neurotransmitter procedure has resulted in serotonin syndrome.